Regulating mitochondrial biogenesis : from herbal remedies to phytomedicine for cancer prevention

Mitochondria are well-adapted endosymbiotic intracellular organelles, acting as the energy supplier for survival and proliferation of cells under aerobic conditions. Moreover, cellular proliferation largely depends on the total number of mitochondria, governed by the process of mitochondrial biogenesis (Davila and Zamorano, 2013; Yoboue et al., 2014).