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One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
- Source :
- Journal of organic chemistry, 82 (6
- Publication Year :
- 2017
-
Abstract
- Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with demonstrated cancer cell antiproliferative activities.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published
Details
- Database :
- OAIster
- Journal :
- Journal of organic chemistry, 82 (6
- Notes :
- No full-text files, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.ocn994546631
- Document Type :
- Electronic Resource