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Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

Authors :
Draisma, G. (Gerrit)
Pool, R. (Reńe)
Kobl, M. (Michael)
Jansen, R. (Rick)
Petersen, A.K.
Vaarhorst, A.A.M. (Anika)
Yet, I. (Idil)
Haller, T. (Toomas)
Demirkan, A. (Ayşe)
Esko, T. (Tõnu)
Zhu, G. (Gu)
Böhringer, S. (Stefan)
Beekman, M. (Marian)
Klinken, J.B. (Jan Bert) van
Römisch-Margl, W. (Werner)
Prehn, C. (Cornelia)
Adamski, J. (Jerzy)
De Craen, A.J.M. (Anton J. M.)
Leeuwen, E.M. (Elisa) van
Amin, N. (Najaf)
Dharuri, H. (Harish)
Westra, H.J. (Harm-Jan)
Franke, L. (Lude)
Geus, E.J.C. (Eco) de
Hottenga, J.J. (Jouke Jan)
Willemsen, G.A.H.M. (Gonneke)
Henders, A.K. (Anjali)
Montgomery, G.W. (Grant)
Dimas, A.S. (Antigone)
Whitfield, J.B. (John B.)
Penninx, B.W.J.H. (Brenda)
Spector, T.D. (Timothy)
Metspalu, A. (Andres)
Slagboom, P.E. (Eline)
Van Dijk, K.W. (Ko Willems)
Hoen, P.A.C. (Peter) 't
Strauch, K. (Konstantin)
Martin, N.G. (Nicholas)
Ommen, G.J. (Gert) van
Illig, T. (Thomas)
Bell, J.T. (Jordana)
Mangino, M. (Massimo)
Suhre, K. (Karsten)
McCarthy, M.I. (Mark)
Gieger, C. (Christian)
Isaacs, A. (Aaron)
Duijn, C.M. (Cornelia) van
Boomsma, D.I. (Dorret)
Draisma, G. (Gerrit)
Pool, R. (Reńe)
Kobl, M. (Michael)
Jansen, R. (Rick)
Petersen, A.K.
Vaarhorst, A.A.M. (Anika)
Yet, I. (Idil)
Haller, T. (Toomas)
Demirkan, A. (Ayşe)
Esko, T. (Tõnu)
Zhu, G. (Gu)
Böhringer, S. (Stefan)
Beekman, M. (Marian)
Klinken, J.B. (Jan Bert) van
Römisch-Margl, W. (Werner)
Prehn, C. (Cornelia)
Adamski, J. (Jerzy)
De Craen, A.J.M. (Anton J. M.)
Leeuwen, E.M. (Elisa) van
Amin, N. (Najaf)
Dharuri, H. (Harish)
Westra, H.J. (Harm-Jan)
Franke, L. (Lude)
Geus, E.J.C. (Eco) de
Hottenga, J.J. (Jouke Jan)
Willemsen, G.A.H.M. (Gonneke)
Henders, A.K. (Anjali)
Montgomery, G.W. (Grant)
Dimas, A.S. (Antigone)
Whitfield, J.B. (John B.)
Penninx, B.W.J.H. (Brenda)
Spector, T.D. (Timothy)
Metspalu, A. (Andres)
Slagboom, P.E. (Eline)
Van Dijk, K.W. (Ko Willems)
Hoen, P.A.C. (Peter) 't
Strauch, K. (Konstantin)
Martin, N.G. (Nicholas)
Ommen, G.J. (Gert) van
Illig, T. (Thomas)
Bell, J.T. (Jordana)
Mangino, M. (Massimo)
Suhre, K. (Karsten)
McCarthy, M.I. (Mark)
Gieger, C. (Christian)
Isaacs, A. (Aaron)
Duijn, C.M. (Cornelia) van
Boomsma, D.I. (Dorret)
Publication Year :
2015

Abstract

Metabolites are small molecules involved in cellular metabolism, which can be detected in biological samples using metabolomic techniques. Here we present the results of genome-wide association and meta-analyses for variation in the blood serum levels of 129 metabolites as measured by the Biocrates metabolomic platfo

Details

Database :
OAIster
Notes :
Nature Communications vol. 6, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn957102458
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1038.ncomms8208