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Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias
- Source :
- Immunity vol.37 (2012) nr.5 p.761-763 [ISSN 1074-7613]
- Publication Year :
- 2012
-
Abstract
- The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.<br />The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.
Details
- Database :
- OAIster
- Journal :
- Immunity vol.37 (2012) nr.5 p.761-763 [ISSN 1074-7613]
- Notes :
- DOI: 10.1016/j.immuni.2012.10.008, Immunity vol.37 (2012) nr.5 p.761-763 [ISSN 1074-7613], English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.ocn931050336
- Document Type :
- Electronic Resource