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Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Authors :
Antoniou, A.C. (Antonis) Spurdle, A.B. (Amanda) Sinilnikova, O. (Olga) Healey, S. (Sue) Pooley, K.A. (Karen) Schmutzler, R.K. (Rita) Versmold, B. (Beatrix) Engel, C. (Christoph) Meindl, A. (Alfons) Arnold, N. (Norbert) Hofmann, W. (Wera) Sutter, C. (Christian) Niederacher, D. (Dieter) Deissler, H. (Helmut) Caldes, T. (Trinidad) Kämpjärvi, K. (Kati) Nevanlinna, H. (Heli) Simard, J. (Jacques) Beesley, J. (Jonathan) Chen, X. (Xiaoqing) Neuhausen, S.L. (Susan) Rebbeck, R. (Timothy) Wagner, T. (Teresa) Lynch, H. (Henry) Isaacs, C. (Claudine) Weitzel, J.N. (Jeffrey) Ganz, P.A. (Patricia) Daly, M.J. (Mark) Tomlinson, G. (Gail) Olopade, O.I. (Olofunmilayo) Blum, J.L. (Joanne) Couch, F.J. (Fergus) Peterlongo, P. (Paolo) Manoukian, S. (Siranoush) Barile, M. (Monica) Radice, P. (Paolo) Szabo, C. (Csilla) Pereira, L.H.M. Greene, M.H. (Mark) Rennert, G. (Gad) Lejbkowicz, F. (Flavio) Barnett-Griness, O. (Ofra) Andrulis, I.L. (Irene) Ozcelik, H. (Hilmi) Gerdes, A-M. (Anne-Marie) Caligo, M.A. (Maria) Laitman, Y. (Yael) Kaufman, B. (Bella) Milgrom, R. (Roni) Friedman, E. (Eitan) Domchek, S.M. (Susan) Nathanson, K.L. (Katherine) Osorio, A. (Ana) Llort, G. (Gemma) Milne, R.L. (Roger) Benítez, J. (Javier) Hamann, U. (Ute) Hogervorst, F.B.L. (Frans) Manders, P. (Peggy) Ligtenberg, M.J. (Marjolijn) Ouweland, A.M.W. (Ans) van den Peock, S. (Susan) Cook, M. (Margaret) Platte, R. (Radka) Evans, D.G. (Gareth) Eeles, R. (Rosalind) Pichert, G. (Gabriella) Chu, C. (Chengbin) Eccles, D. (Diana) Davidson, R. (Rosemarie) Douglas, F. (Fiona) Godwin, A.K. (Andrew) Mazoyer, S. (Sylvie) Sobol, H. (Hagay) Bourdon, V. (Violaine) Eisinger, F. (François) Chompret, A. (Agnès) Barjhoux, L. (Laure) Capoulade, C. (Corinne) Bressac-de Paillerets, B. (Brigitte) Lenoir, G.M. (Gilbert) Gauthier-Villars, M. (Marion) Houdayer, C. (Claude) Stoppa-Lyonnet, D. (Dominique) Chenevix-Trench, G. (Georgia) Easton, D.F. (Douglas) Antoniou, A.C. (Antonis) Spurdle, A.B. (Amanda) Sinilnikova, O. (Olga) Healey, S. (Sue) Pooley, K.A. (Karen) Schmutzler, R.K. (Rita) Versmold, B. (Beatrix) Engel, C. (Christoph) Meindl, A. (Alfons) Arnold, N. (Norbert) Hofmann, W. (Wera) Sutter, C. (Christian) Niederacher, D. (Dieter) Deissler, H. (Helmut) Caldes, T. (Trinidad) Kämpjärvi, K. (Kati) Nevanlinna, H. (Heli) Simard, J. (Jacques) Beesley, J. (Jonathan) Chen, X. (Xiaoqing) Neuhausen, S.L. (Susan) Rebbeck, R. (Timothy) Wagner, T. (Teresa) Lynch, H. (Henry) Isaacs, C. (Claudine) Weitzel, J.N. (Jeffrey) Ganz, P.A. (Patricia) Daly, M.J. (Mark) Tomlinson, G. (Gail) Olopade, O.I. (Olofunmilayo) Blum, J.L. (Joanne) Couch, F.J. (Fergus) Peterlongo, P. (Paolo) Manoukian, S. (Siranoush) Barile, M. (Monica) Radice, P. (Paolo) Szabo, C. (Csilla) Pereira, L.H.M. Greene, M.H. (Mark) Rennert, G. (Gad) Lejbkowicz, F. (Flavio) Barnett-Griness, O. (Ofra) Andrulis, I.L. (Irene) Ozcelik, H. (Hilmi) Gerdes, A-M. (Anne-Marie) Caligo, M.A. (Maria) Laitman, Y. (Yael) Kaufman, B. (Bella) Milgrom, R. (Roni) Friedman, E. (Eitan) Domchek, S.M. (Susan) Nathanson, K.L. (Katherine) Osorio, A. (Ana) Llort, G. (Gemma) Milne, R.L. (Roger) Benítez, J. (Javier) Hamann, U. (Ute) Hogervorst, F.B.L. (Frans) Manders, P. (Peggy) Ligtenberg, M.J. (Marjolijn) Ouweland, A.M.W. (Ans) van den Peock, S. (Susan) Cook, M. (Margaret) Platte, R. (Radka) Evans, D.G. (Gareth) Eeles, R. (Rosalind) Pichert, G. (Gabriella) Chu, C. (Chengbin) Eccles, D. (Diana) Davidson, R. (Rosemarie) Douglas, F. (Fiona) Godwin, A.K. (Andrew) Mazoyer, S. (Sylvie) Sobol, H. (Hagay) Bourdon, V. (Violaine) Eisinger, F. (François) Chompret, A. (Agnès) Barjhoux, L. (Laure) Capoulade, C. (Corinne) Bressac-de Paillerets, B. (Brigitte) Lenoir, G.M. (Gilbert) Gauthier-Villars, M. (Marion) Houdayer, C. (Claude) Stoppa-Lyonnet, D. (Dominique) Chenevix-Trench, G. (Georgia) Easton, D.F. (Douglas)
Publication Year :
2008
Abstract
Germline mutations in BRCA1 and BRCA2 confer high risks of breast cancer. However, evidence suggests that these risks are modified by other genetic or environmental factors that cluster in families. A recent genome-wide association study has shown that common alleles at single nucleotide polymorphisms (SNPs) in FGFR2 (rs29
Details
Database :
OAIster
Notes :
American Journal of Human Genetics vol. 82 no. 4, pp. 937-948, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn929973047
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1016.j.ajhg.2008.02.008