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Large-scale evidence for the effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS study
- Publication Year :
- 2006
-
Abstract
- Background: Osteoporosis and fracture risk are considered to be under genetic control. Extensive work is being performed to identify the exact genetic variants that determine this risk. Previous work has suggested that a G/T polymorphism affecting an Sp1 binding site in the COLIA1 gene is a genetic marker for low bone mineral density (BMD) and osteoporotic fracture, but there have been no very-large-scale studies of COL
Details
- Database :
- OAIster
- Notes :
- application/pdf, PLoS Medicine vol. 3 no. 4, pp. 515-523, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.ocn929963118
- Document Type :
- Electronic Resource
- Full Text :
- https://doi.org/10.1371.journal.pmed.0030090