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Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis
- Publication Year :
- 2014
-
Abstract
- Background: Colorectal adenomatous polyposis is associated with a high risk of colorectal cancer (CRC) and is frequently caused by germline mutations in APC or MUTYH. However, in about 20-30% of patients no underlying gene defect can be identified. In this study, we tested if recently identified CRC risk variants play a role in patients with >10 adenomas. Methods We analysed a total of 16 SNPs with a reported association with CR
Details
- Database :
- OAIster
- Notes :
- Journal of Medical Genetics vol. 51 no. 1, pp. 55-60, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.ocn929958472
- Document Type :
- Electronic Resource
- Full Text :
- https://doi.org/10.1136.jmedgenet-2013-102000