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Two new aromadendrane sesquiterpenes from the stem Bark of Alafia multiflora

Authors :
Tchinda, Alembert A.T.
Nga, Nnanga
Tsala, David Emery
Cieckiewicz, Ewa
Frédérich, Michel
Kiss, Robert
Connolly, Joseph J.D.
Tchinda, Alembert A.T.
Nga, Nnanga
Tsala, David Emery
Cieckiewicz, Ewa
Frédérich, Michel
Kiss, Robert
Connolly, Joseph J.D.
Source :
Natural Product Communications, 9 (12
Publication Year :
2014

Abstract

Two new aromadendrane sesquiterpenoids (1β,4β,5α,6α,7α,11S)-aromadendr-9-en-13,14-dioic acid (1) and (1?4?5?6?7?11S)-13-oxoaromadendr-9-en- 14-oic acid (2) have been isolated from the stem bark of Alafia multiflora along with β-sitosterol and β-sitosterol glucoside. Their structures were established on the basis of spectroscopic analyses, including 1D and 2D NMR experiments (1H-1H COSY, NOESY, HSQC, HMBC). Compound 1 showed a weak growth inhibitory activity against the murine melanoma line B16F10 MTT.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Natural Product Communications, 9 (12
Notes :
No full-text files, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn908363307
Document Type :
Electronic Resource