Assays of urinary corticoids : a comparison between results of chemical and biological methods

"The experimental data which will be presented consist of estimations on urine samples of normal humans and of patients suffering from a variety of clinical conditions. The urines have been assayed by a biological and by a chemical method, both of which purport to measure substances similar to those isolated from the adrenal cortex. The chief purpose of this undertaking was to define the correlation between the results of the bio as say and chemical assay on each sample of urine. A secondary purpose was to determine the suitability of these methods (particularly the chemical method) for use in hospital laboratories as tools to aid clinicians in their assessment of adrenal cortical function for the diagnosis and management of the individual patients. ..."