Ultrastructural visualization of Cabot rings in pernicious anemia

Authors :: Department of Internal Medicine, Simpson Memorial Institute, Medical School, 48109, Ann Arbor, Michigan, USA; The Cellular Chemistry Laboratory, Department of Environmental and Industrial Health, School of Public Health, The University of Michigan, 48109, Ann Arbor, Michigan, USA
Ann Arbor
Kass, Lawrence
Gray, R.H.
Department of Internal Medicine, Simpson Memorial Institute, Medical School, 48109, Ann Arbor, Michigan, USA; The Cellular Chemistry Laboratory, Department of Environmental and Industrial Health, School of Public Health, The University of Michigan, 48109, Ann Arbor, Michigan, USA
Ann Arbor
Kass, Lawrence
Gray, R.H.
Publication Year :: 2006
Abstract: Using the ammoniacal silver stain, Cabot rings were identified in peripheral blood erythrocytes from patients with severe untreated pernicious anemia. Ultrastructural studies of these erythrocytes showed silver deposits in partial loops and figure-eight forms, indicating that arginine rich histone may be a prominent component of the Cabot ring.

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