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Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.

Authors :
Prévot, Pierre-Paul
Augereau, Cécile
Simion, Alexandru
Van Den Steen, Géraldine
Dauguet, Nicolas
Lemaigre, Frédéric P
Jacquemin, Patrick
Prévot, Pierre-Paul
Augereau, Cécile
Simion, Alexandru
Van Den Steen, Géraldine
Dauguet, Nicolas
Lemaigre, Frédéric P
Jacquemin, Patrick
Source :
Gastroenterology, 145 (3
Publication Year :
2013

Abstract

Diseases of the exocrine pancreas are often associated with perturbed differentiation of acinar cells. MicroRNAs (miRNAs) regulate pancreas development, yet little is known about their contribution to acinar cell differentiation. We aimed to identify miRNAs that promote and control the maintenance of acinar differentiation.<br />Journal Article<br />Research Support, Non-U.S. Gov't<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Gastroenterology, 145 (3
Notes :
No full-text files, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn893993211
Document Type :
Electronic Resource