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Recommendations for the treatment of epilepsies in general practice in Belgium

Authors :
Boon, Paul
Engelborghs, Sebastiaan
Hauman, Henri
Jansen, An
Lagae, Lieven
Legros, Benjamin
Ossemann, Michel
Sadzot, Bernard
Urbain, Etienne
Van Rijckevorsel, Kenou
Boon, Paul
Engelborghs, Sebastiaan
Hauman, Henri
Jansen, An
Lagae, Lieven
Legros, Benjamin
Ossemann, Michel
Sadzot, Bernard
Urbain, Etienne
Van Rijckevorsel, Kenou
Source :
Acta neurologica belgica, 108 (4
Publication Year :
2008

Abstract

The large choice of antiepileptic drugs (AEDs) in Belgium complicates the selection of the appropriate product for the individual patient. International guide-lines on the treatment of epilepsy have been published, but are not tailored to the Belgian situation. This publication presents recommendations from a group of Belgian epilepsy experts for the practical management of epilepsy in general practice in Belgium. It includes recommendations for initial monotherapy and add-on treatment in adult patients (≥ 16 years) and initial monotherapy in paediatric patients (< 16 years). For these three situations a first choice AED is recommended. One or more alternative first choice AEDs are defined for patients in which certain patient- or AED-related factors preclude the use of the first choice product. Selection of compounds was based on the registration and reimbursement status in Belgium, the level of evidence of efficacy, common daily practice and the personal views and experiences of the authors. The paper reflects the situation in 2008. In addition to the treatment recommendations, other relevant points to consider in the treatment of epilepsy with AEDs are addressed, including comorbidity and age of the patient, the interaction potential, pharmacokinetic properties and safety profile of the AEDs, and generic substitution.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Acta neurologica belgica, 108 (4
Notes :
No full-text files, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn893984066
Document Type :
Electronic Resource