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Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events
- Source :
- Haastrup , E , Bukh , J O D , Bock , C , Vinberg , M , Thørner , L W , Hansen , T , Werge , T , Kessing , L V & Ullum , H 2012 , ' Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events ' , Journal of Affective Disorders , vol. 136 , no. 1-2 , pp. 134-138 .
- Publication Year :
- 2012
-
Abstract
- Depression is accompanied by an inflammatory reaction and activation of cell mediated immunity (CMI) and stressors may induce the cytokine network in humans. The proinflammatory cytokine interleukin-18 (IL-18) is less investigated in depression but highly relevant since it is produced by activated macrophages and expressed in the brain.
Details
- Database :
- OAIster
- Journal :
- Haastrup , E , Bukh , J O D , Bock , C , Vinberg , M , Thørner , L W , Hansen , T , Werge , T , Kessing , L V & Ullum , H 2012 , ' Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events ' , Journal of Affective Disorders , vol. 136 , no. 1-2 , pp. 134-138 .
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.ocn842755899
- Document Type :
- Electronic Resource