Back to Search Start Over

Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts.

Authors :
Gillard, Pieter
Ling, Zhidong
Mathieu, Chantal
Crenier, Laurent
Lannoo, Matthias
Maes, Bart
Roep, Bart
Gorus, Frans
Pipeleers, Daniel
Keymeulen, Bart
Gillard, Pieter
Ling, Zhidong
Mathieu, Chantal
Crenier, Laurent
Lannoo, Matthias
Maes, Bart
Roep, Bart
Gorus, Frans
Pipeleers, Daniel
Keymeulen, Bart
Source :
Transplantation, 85 (2
Publication Year :
2008

Abstract

One year survival of islet cell grafts has been reproducibly achieved under combination immune therapy including tacrolimus (TAC). However, the use of TAC causes beta-cell and renal toxicity. Because sirolimus (SIR) monotherapy was successful in kidney transplantation under antithymocyte globulin (ATG), we undertook a pilot study comparing SIR monotherapy with SIR-TAC combination therapy.<br />Clinical Trial<br />Comparative Study<br />Journal Article<br />Research Support, Non-U.S. Gov't<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Transplantation, 85 (2
Notes :
No full-text files, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn837147618
Document Type :
Electronic Resource