FURTHER EXPERIMENTAL AND CLINICAL OBSERVATIONS ON HEMORRHAGIC SHOCK

Measurements of blood volume in c rdiovascular surgical patie s indicated good correlation of postopera iv mea urements with preoperativ values when the p tients were s able, but were in considerable error when vital signs were unstabl , or when vasopressor sub tances were being adminis ere . In the absence of clinical evide ce of heart is a e, c rdiac output an coron ry blood flow were w ll maintaine in the postsurgical period. Myoc rdial blood flow nd c r i c output m asure ent in pati n s wit acute hemorrhagic an traumatic s ock incre e in pati ts below age 40 and were essentially unchanged from the predicted value in patients over 40. In dogs subjected to hemorrhagic shock discrepa cies of measured blood volume after shock has intervened with volumes known to xi t in the animal obtained by substracting volume of shed blood from pres ock measured volume c nno be e pl in d by tracers of plas a, of red cells, or of tracers of plasma and red cells combined Lig tions of art ries to the extremities d to the gastrointestinal ract do not protect the nimal from hemorrhagic shock. (Author)