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The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

Authors :
Grarup, N
Overvad, M
Sparsø, T
Witte, D R
Pisinger, C
Jørgensen, Torben
Yamauchi, T
Hara, K
Maeda, S
Kadowaki, T
Hansen, T
Pedersen, Oluf
Grarup, N
Overvad, M
Sparsø, T
Witte, D R
Pisinger, C
Jørgensen, Torben
Yamauchi, T
Hara, K
Maeda, S
Kadowaki, T
Hansen, T
Pedersen, Oluf
Source :
Grarup , N , Overvad , M , Sparsø , T , Witte , D R , Pisinger , C , Jørgensen , T , Yamauchi , T , Hara , K , Maeda , S , Kadowaki , T , Hansen , T & Pedersen , O 2011 , ' The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals ' , Diabetologica , vol. 54 , no. 4 , pp. 789-94 .
Publication Year :
2011

Abstract

A genome-wide association study in the Japanese population reported two genome-wide significant loci associated with type 2 diabetes of which the VPS13C/C2CD4A/C2CD4B locus was replicated in Europeans. We looked for potential associations between the diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant and diabetes-related intermediary traits.

Details

Database :
OAIster
Journal :
Grarup , N , Overvad , M , Sparsø , T , Witte , D R , Pisinger , C , Jørgensen , T , Yamauchi , T , Hara , K , Maeda , S , Kadowaki , T , Hansen , T & Pedersen , O 2011 , ' The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals ' , Diabetologica , vol. 54 , no. 4 , pp. 789-94 .
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn826479386
Document Type :
Electronic Resource