Coexistence of Papillary Carcinoma and Hashimoto's Thyroiditis

The aim of the study was to determine the incidence of coexistence of papillary carcinoma and Hashimoto's thyroiditis in cytologic material. Cytologic findings were collected from 10508 patients that underwent ultrasound-guided fine needle aspiration cytology (FNAC) of the thyroid. Hashimoto's thyroiditis was found in 2156 (20.5%) and papillary carcinoma in 269 (2.6%) of 10508 patients with FNAC, whereas both Hashimoto's thyroiditis and papillary carcinoma were present in 42 (0.4%) patients. Among patients with FNAC diagnosis of Hashimoto's thyroiditis, the prevalence of papillary carcinoma was 1.9%. Among patients with FNAC diagnosis of papillary carcinoma, the prevalence of Hashimoto's thyroiditis was 15.6%. There was no statistically significant association between the presence of papillary carcinoma and Hashimoto's thyroiditis in patients undergoing FNAC (p=0.0522). In conclusion, in a large series of patients, the incidence of Hashimoto's thyroiditis and papillary carcinoma coexistence in cytologic material was 0.4%. There was no statistically significant relationship between Hashimoto's thyroiditis and papillary carcinoma in cytologic material.
Cilj ove studije bio je utvrditi incidenciju istodobne prisutnosti papilarnog karcinoma i Hashimotova tireoiditisa u citološkim uzorcima. Prikupljeni su citološki nalazi za 10.508 bolesnika podvrgnutih ultrazvučnoj citološkoj punkciji štitnjače tankom iglom (FNAC). Hashimotov tiroiditis je utvrđen kod 2156 (20,5%), a papilarni karcinom kod 269 (2,6%) od tih 10.508 bolesnika, dok je 42 (0,4%) bolesnika imalo i papilarni karcinom i Hashimotov tiroiditis. U bolesnika s Hashimotovim tireoiditisom učestalost papilarnog karcinoma bila je 1,9%, a među bolesnicima s papilarnim karcinomom učestalost Hashimotova tireoiditsa bila je 15,6%. Kod bolesnika podvrgnutih FNAC nije bilo statistički značajne povezanosti između prisutnosti papilarnog karcinoma i Hashimotova tireoiditisa (p=0,0522). Dakle, u citološkom materijalu velikog niza bolesnika utvrđena je incidencija istodobne prisutnosti papilarnog karcinoma i Hashimotova tiroiditisa od 0,4%. U citološkim uzorcima nije utvrđena statistički značajna povezanost između Hashimotova tireoiditisa i papilarnog karcinoma.