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Failure of metoclopramide to control emesis or nausea due to stressful angular or linear acceleration
- Source :
- Aviation, Space, and Environmental Medicine. 58
- Publication Year :
- 1987
- Publisher :
- United States: NASA Center for Aerospace Information (CASI), 1987.
-
Abstract
- Orally administered metoclopramide (REGLAN) at doses of 10 or 20 mg, 75 min prior to either stressful linear acceleration (parabolic flight) or cross-coupled accelerative semicircular canal stimulation in a rotating chair was evaluated for its ability to prevent emesis or nausea II, respectively. Although metoclopramide is an effective antiemetic agent that enhances gastric emptying and prevents cancer chemotherapy-induced emesis, it was not possible to demonstrate any significant (p less than 0.05) effects of this drug on motion sickness.
- Subjects :
- Aerospace Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 00956562
- Volume :
- 58
- Database :
- NASA Technical Reports
- Journal :
- Aviation, Space, and Environmental Medicine
- Publication Type :
- Report
- Accession number :
- edsnas.19870044421
- Document Type :
- Report