P04-41. Kinetics of Antibody Neutralization and Viral Evolution Following Envelope Vaccination in SIV-infected Rhesus Monkeys

Authors :: Basavapathruni, A
Coffey, R
Hraber, P
Giri, A
Mascola, J
Nabel, G
Korber, B
Yeh, Wendy Wen-Li
Whitney, James B.
Rao, Sowmya R.
Seaman, Michael S.
Letvin, Norman Lee
Source :: Basavapathruni, A, W Yeh, R Coffey, J Whitney, P Hraber, A Giri, S Rao, et al. 2009. P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys. Retrovirology 6(Suppl 3): P69.
Publication Year :: 2009
Publisher :: BioMed Central, 2009.
Abstract: Poster presentation. Conclusion: Our results indicate that env vaccination is associated with an accelerated development of autologous neutralizing antibodies. These antibodies were focused at least in part on the V1 region of Env, since there was selective pressure in this region of the envelope for the evolution of mutational changes.

Language :: English
ISSN :: 17424690
Database :: Digital Access to Scholarship at Harvard (DASH)
Journal :: Basavapathruni, A, W Yeh, R Coffey, J Whitney, P Hraber, A Giri, S Rao, et al. 2009. P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys. Retrovirology 6(Suppl 3): P69.
Publication Type :: Academic Journal
Accession number :: edshld.1.4706588
Document Type :: Journal Article
Full Text :: https://doi.org/10.1186/1742-4690-6-S3-P69

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