The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

Authors :: Egan, Michael F.
Kojima, Masami
Callicott, Joseph H.
Goldberg, Terry E.
Kolachana, Bhaskar S.
Bertolino, Alessandro
Zaitsev, Eugene
Gold, Bert
Goldman, David
Dean, Michael
Lu, Bai
Weinberger, Daniel R.
Source :: Cell. Jan 24, 2003, Vol. 112 Issue 2, 257-269
Publication Year :: 2003
Abstract: Research has been conducted on brain-derived neurotrophic factor. The role of valine to methionine substitution in the 5' pro-region of the human brain-derived neurotrophic factor proteins has been investigated, and the results are described.

Subjects :: Cell research -- Analysis
Secretion -- Genetic aspects
Secretion -- Physiological aspects
Hippocampus (Brain) -- Genetic aspects
Hippocampus (Brain) -- Physiological aspects
Neurons -- Physiological aspects
Methionine -- Physiological aspects
Proteins -- Physiological aspects
Brain-derived neurotrophic factor -- Research
Biological sciences

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