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Association of serum digoxin concentration and outcomes in patients with heart failure

Authors :
Rathore, Saif S.
Curtis, Jeptha P.
Wang, Yongfei
Bristow, Michael R.
Krumholz, Harlan M.
Source :
JAMA, The Journal of the American Medical Association. Feb 19, 2003, Vol. 289 Issue 7, p871, 8 p.
Publication Year :
2003

Abstract

Patients with congestive heart failure who are taking digoxin should have the dose adjusted to produce a blood level between 0.5 and 0.8 nanograms per milliliter. Blood levels higher than that may increase their risk of death, according to a study of 3,782 patients. All of the men in the study had a left ventricular ejection fraction of 45% or less.

Details

ISSN :
00987484
Volume :
289
Issue :
7
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.98196025