Association of serum digoxin concentration and outcomes in patients with heart failure

Authors :: Rathore, Saif S.
Curtis, Jeptha P.
Wang, Yongfei
Bristow, Michael R.
Krumholz, Harlan M.
Source :: JAMA, The Journal of the American Medical Association. Feb 19, 2003, Vol. 289 Issue 7, p871, 8 p.
Publication Year :: 2003
Abstract: Patients with congestive heart failure who are taking digoxin should have the dose adjusted to produce a blood level between 0.5 and 0.8 nanograms per milliliter. Blood levels higher than that may increase their risk of death, according to a study of 3,782 patients. All of the men in the study had a left ventricular ejection fraction of 45% or less.

Subjects :: Congestive heart failure -- Patient outcomes
Congestive heart failure -- Drug therapy
Digoxin -- Adverse and side effects
Digoxin -- Dosage and administration

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