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Unusual benefits of macromolecular shielding by polyethylene glycol for reactions at the diffusional limit: tha case of factor VIIai and tissue factor

Authors :
Stone, Matthew
Harvey, Stephen B.
Kisiel, Walter
Foster, Donald
Nelsestuen, Gary L.
Source :
Biochemistry. Dec 31, 2002, Vol. 41 Issue 52, p15820, 6 p.
Publication Year :
2002

Abstract

Research has been conducted on polyethylene glycol. The effect of polyethylene glycol modification on circulation lifetime and activity of factor VIIai and the properties of polyethylene glycol-modified proteins have been investigated and discussed.

Subjects

Subjects :
Biochemistry -- Research
Macromolecules -- Physiological aspects
Polyethylene glycol -- Physiological aspects
Chemical reactions -- Analysis
Solution (Chemistry) -- Physiological aspects
Proteins -- Physiological aspects
Biological sciences
Chemistry

Details

ISSN :
00062960
Volume :
41
Issue :
52
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.97067173

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