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Interaction of tubulin with a new fluorescent analogue of vinblastine

Authors :
Chatterjee, Sabarni K.
Patel, Pruthvi
Ravindra, Rudravajhala
Qin, Yong
Kuehne E.
Bane, Susan L.
Laffray, Julien
Source :
Biochemistry. Nov 26, 2002, Vol. 41 Issue 47, p14010, 9 p.
Publication Year :
2002

Abstract

Research has been conducted on the antimitotic agent vinblastine used in cancer chemotherapy. The preparation of vinblastine derivative which retains high affinity for tubulin is described.

Details

ISSN :
00062960
Volume :
41
Issue :
47
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.96266749