Proteolytic cleavage of he THR subunit during anaphase limits Drosophila separase function

Proteolytic cleavage of the Three rows protein (THR) subunit during anaphase has been found to limit Drosophila separase function. THR cleavage is especially important during the process of cellularization, which is after completion of the last syncytial mitosis of early embryogenesis. This suggests that Drosophila separase has targets in addition to cohesin subunits.