Lewis acid-activated chiral leaving group: enantioselective electrophilic addition to prochiral olefins

Authors :: Nakamura, Hiroko
Ishihara, Kazuaki
Yamamoto, Hisashi
Source :: Journal of Organic Chemistry. July 26, 2002, Vol. 67 Issue 15, p5124, 14 p.
Publication Year :: 2002
Abstract: Research has been conducted on the prochiral olefins. The strategy developed for the enantioselective alkylation of these olefins using a chiral leaving group and Lewis acid is described.

Subjects :: Chemistry, Organic -- Research
Acids -- Physiological aspects
Chirality -- Physiological aspects
Enantiomers -- Physiological aspects
Olefins -- Physiological aspects
Ring formation (Chemistry) -- Physiological aspects
Alkylation -- Physiological aspects
Biological sciences
Chemistry

Tools