Amphidinolides H2-H5, G2, and G3, new cytotoxic 26- and 27-membered macrolides from dinoflagellate Amphidinium sp

Research has been conducted on the macrolides amphidinolides. The isolation of these amphidinolides from the marine dinoflagellate Amphidinium sp. has been carried out and the results indicate that the presence of allyl epoxide and the ketone at C-20 is important for the amphidinolides' cytotoxicity.