Asymmetric synthesis of 1,2,3-trisubstituted cyclopentanes and cyclohexanes as key components of substance P antagonists

Authors :: Kuethe, Jeffrey T.
Wong, Audrey
Wu, Jimmy
Davies, Ian W.
Dormer, Peter G.
Welch, Christopher J.
Hillier, Michael C.
Hughes, David L.
Reider, Paul J.
Source :: Journal of Organic Chemistry. August 23, 2002, Vol. 67 Issue 17, p5993, 8 p.
Publication Year :: 2002
Abstract: Research has been conducted on the 1,2,3-trisubstituted cyclohexanes and cyclopentanes. The results of the asymmetric synthesis of these compounds developed for the preparation of the 2,3-disubstituted cyclohexenones and cyclopentenones are presented.

Subjects :: Chemistry, Organic -- Research
Substitution reactions -- Analysis
Cyclic compounds -- Physiological aspects
Hexane -- Physiological aspects
Chemical inhibitors -- Physiological aspects
Biological sciences
Chemistry

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