Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons

Authors :: Sugitani, Yoshinobu
Nakai, Shigeyasu
Minowa, Osamu
Nishi, Miyuki
Jishage, Kou-ichi
Kawano, Hitoshi
Mori, Kensaku
Ogawa, Masaharu
Noda, Tetsuo
Source :: Genes & Development. July 15, 2002, Vol. 16 Issue 14, p1760, 6 p.
Publication Year :: 2002
Abstract: Research has been conducted on homeodomain proteins Brn-1 and Brn-2 coexpressed in the developing neocortex. Results indicate that the double disruption of Brn-1 and Brn-2 genes leads to the abnormal neocortex formation.

Subjects :: Genetic research -- Analysis
Neocortex -- Genetic aspects
Neurons -- Genetic aspects
Gene expression -- Physiological aspects
Proteins -- Genetic aspects
Biological sciences

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