Exclusive alpha-coupling in the aldol reaction of unsaturated trimethylsilyl esters: an efficient and practical direct synthesis of unsaturated beta-hydroxy acids

Authors :: Bellassoued, Moncef
Grugier, Jerome
Lensen, Nathalie
Catherine, Audrey
Source :: Journal of Organic Chemistry. August 9, 2002, Vol. 67 Issue 16, p5611, 5 p.
Publication Year :: 2002
Abstract: Research has been conducted on the free unsaturated beta-hydroxy acids. The utility of the lithio thimethylsilyl butenoates used as reagents for the synthesis of these beta-hydroxy acids has been tested and the details are reported.

Subjects :: Chemistry, Organic -- Research
Chemical reactions -- Analysis
Acids -- Physiological aspects
Chemical tests and reagents -- Physiological aspects
Lithium -- Physiological aspects
Biological sciences
Chemistry

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