Is an iodine atom almighty as a leaving group for Bu (sub)3 SnH-mediated radical cyclization? The effect of a halogen atom on the 5-endo-trig radical cyclization of N-vinyl-alpha-halo amides

Authors :: Tamura, Osamu
Matsukida, Hana
Toyao, Atsushi
Takeda, Yoshifumi
Ishibashi, Hiroyuki
Source :: Journal of Organic Chemistry. August 9, 2002, Vol. 67 Issue 16, p5537, 9 p.
Publication Year :: 2002
Abstract: Research has been conducted on the halogen atoms. The role of this atom as a leaving group in Bu (sub)3 SnH-mediated radical cyclization of N-(cyclohex-1-enyl) alpha-halo amides has been investigated and the details are reported.

Subjects :: Chemistry, Organic -- Research
Iodine -- Physiological aspects
Radicals (Chemistry) -- Physiological aspects
Ring formation (Chemistry) -- Physiological aspects
Tin -- Physiological aspects
Hydrogen -- Physiological aspects
Halogens -- Physiological aspects
Amides -- Physiological aspects
Biological sciences
Chemistry

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