Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

Authors :: Fingar, Diane C.
Salama, Sofie
Tsou, Christina
Harlow, Ed
Blenis, John
Source :: Genes & Development. June 15, 2002, Vol. 16 Issue 12, p1472, 16 p.
Publication Year :: 2002
Abstract: Research has been conducted on the cell cycle and cell growth. The role of the mammalian TOR in mammalian physiology has been investigated and the use of the cultured cell system in examining the biochemical signaling pathways regulating proliferating mammalian cell size is discussed.

Subjects :: Genetic research -- Analysis
Cells -- Growth
Cell cycle -- Genetic aspects
Biosynthesis -- Physiological aspects
Biological sciences

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