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A mutational analysis of the PD...D/EXK motif suggests that McrC harbors the catalytic center for DNA cleavage by the GTP-dependent restriction enzyme McrBC from Escherichia coli
- Source :
- Biochemistry. April 23, 2002, Vol. 41 Issue 16, p5236, 9 p.
- Publication Year :
- 2002
-
Abstract
- The mutational analysis of the presumptive nucleolytic center of McrC subunit of the McrBC system of Escherichia coli suggests that McrC mediates DNA cleavage by McrBC. The catalytic center of the McrC is represented by the sequence TD(sup)224 ....D(sup)257 AK.
Details
- ISSN :
- 00062960
- Volume :
- 41
- Issue :
- 16
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.86433500