Testosterone administration to older men improves muscle function: molecular and physiological mechanisms

Authors :: Ferrando, Arny A.
Sheffield-Moore, Melinda
Yeckel, Catherine W.
Gilkison, Charles
Jiang, Jie
Achacosa, Alison
Lieberman, Steven A.
Tipton, Kevin
Wolfe, Robert R.
Urban, Randall J.
Source :: The American Journal of Physiology. March, 2002, Vol. 282 Issue 3, pE601, 7 p.
Publication Year :: 2002
Abstract: We investigated the effects of 6 mo of near-physiological testosterone administration to older men on skeletal muscle function and muscle protein metabolism. Twelve older men ([greater than or equal to] 60 yr) with serum total testosterone concentrations aging; muscle strength; lean body mass; insulin-like growth factor I

Subjects :: Aged men -- Physiological aspects
Testosterone -- Health aspects
Muscle proteins -- Physiological aspects
Insulin-like growth factors -- Analysis
Muscle strength -- Evaluation
Biological sciences

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