Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

Authors :: Joo, Woo S.
Jeffrey, Philip D.
Cantor, Sharon B.
Finnin, Michael S.
Livingston, David M.
Pavletich, Nikola P.
Source :: Genes & Development. March 1, 2002, Vol. 16 Issue 5, p583, 11 p.
Publication Year :: 2002
Abstract: Research has been conducted on the Brca1 C-terminal domains, protein-protein interaction motif in the proteins involved in the DNA damage response and DNA repair. The structures of the human 53BP1-p53 complex and of the rat Brac1 BRCT repeats are described.

Subjects :: Genetic research -- Analysis
Proteins -- Genetic aspects
DNA damage -- Genetic aspects
DNA repair -- Genetic aspects
Biological sciences

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