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The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol
The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol
- Source :
- Biochemistry. March 12, 2002, Vol. 41 Issue 10, p3405, 9 p.
- Publication Year :
- 2002
-
Abstract
- Research has been conducted on the ricin A chain, protein toxins entering mammalian cells via endocytosis. The hypothesis that the lysine paucity reduces the chance of ubiquitination and ubiquitin-mediated proteasomal degradation has been investigated and the results are reported.
Details
- ISSN :
- 00062960
- Volume :
- 41
- Issue :
- 10
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.84155146