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Intestinal absorption and lymphatic transport of a high [gamma]-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. (Nutrient Metabolism--Research Communication)
- Source :
- The Journal of Nutrition. Feb, 2002, Vol. 132 Issue 2, p218, 4 p.
- Publication Year :
- 2002
-
Abstract
- A new canola strain capable of producing >30% [gamma]-linolenic acid [GLA, 18:3(n-6)] in the seed oil has been developed in our laboratories. This study compares the intestinal absorption and lymphatic transport of this newly developed high GLA content canola oil (HGCO) with traditional GLA-rich borage oil (BO) using a lymph fistula rat model. To assess the extent that 1 mL of GLA in the supplemented oil was absorbed and transported, the fatty acid compositions of triglycerides in mesenteric lymph were compared over a 24-h collection period. The digestion, uptake and lymphatic transport of HGCO and the normal physiologic changes associated with fat absorption (e.g., lymph flow and an increase in lymphatic endogenous lipids outputs, triglycerides, cholesterol and phospholipids) were similar in the HGCO-and the BO-fed rats. The original differences in [gamma]-linolenic acid content in HGCO and BO were preserved in the fatty acid composition of the rats' lymph lipid. We conclude that the HGCO derived from the genetically modified canola plant is absorbed and transported into lymph similarly to BO. J. Nutr. 132: 218-221, 2002. KEY WORDS: * [gamma]-linolenic acid * intestinal lipid absorption * genetically modified canola oil * lymphatic lipids * rats
Details
- ISSN :
- 00223166
- Volume :
- 132
- Issue :
- 2
- Database :
- Gale General OneFile
- Journal :
- The Journal of Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.83520380