Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle

Authors :: Wojtaszewski, Jorgen F.P.
Jorgensen, Sebastian B.
Hellsten, Ylva
Hardie, D. Grahame
Richter, Erik A.
Source :: Diabetes. February 2002, Vol. 51 Issue 2, p284, 9 p.
Publication Year :: 2002
Abstract: 5'-AMP-activated protein kinase (AMPK) functions as a metabolic switch in mammalian cells and can be artificially activated by 5-aminoimidazole-4-carboxamide (AICA)-riboside. AMPK activation during muscle contraction is dependent on muscle glycogen [...]

Subjects :: Diabetes -- Research
Striated muscle -- Physiological aspects -- Research
Protein kinases -- Physiological aspects -- Research
Glycogen -- Synthesis
Electronegativity -- Physiological aspects -- Research
Health
Physiological aspects
Research

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