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Lithiation of 2-heterosubstituted pyridines with BuLi-LiDMAE: evidenve for regiospecificity at C-6

Authors :
Gros, Philippe
Choppin, Sabine
Mathieu, Julien
Fort, Yves
Source :
Journal of Organic Chemistry. Jan 11, 2002, Vol. 67 Issue 1, p234, 4 p.
Publication Year :
2002

Abstract

Research has been conducted on the 2-chloro- and 2-methoxypyridine. The initial deprotonation site of these compounds during the reaction with BuLi-Me (sub)2 N(CH (sub)2) (sub)2 OLi has been determined and the details are reported.

Details

ISSN :
00223263
Volume :
67
Issue :
1
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.82331694