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Recognizing phosphatidylinositol 3-phosphate
- Source :
- Cell. Nov 30, 2001, Vol. 107 Issue 5, p559, 4 p.
- Publication Year :
- 2001
-
Abstract
- The role of lipids in signal transduction with reference to phosphatidylinositol 3-phosphate directing endosomal localization of regulatory proteins is discused. Specific phosphate and hydroxyl group interactions distinguish phosphatidylinositol 3-phosphate from other lipids. The lipid binds to FYVE and PX domains found in intracellular membrane transport/signal transduction proteins and phagocyte proteins, respectively.
Details
- ISSN :
- 00928674
- Volume :
- 107
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.81571501