LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development

Authors :: Gong, Yaoquin
Slee, Roger B.
Fukai, Naomi
Rawadi, Georges
Roman-Roman, Sergio
Reginato, Anthony M.
Wang, Hongwei
Cundy, Tim
Glorieux, Frencis H.
Lev, Dorit
Zucharin, Margaret
Oexle, Konrad
Marcelino, Jose
Suwairi, Wafaa
Heeger, Shauna
Sabatakos, George
Apte, Suneel
Adkins, William N.
Allgrove
Aeslan-Kirshner, Mine
Batch, Jennifer A.
Beighton, Peter
Black, Graeme C. M.
Boles, Richard G.
Boon, Laurence M.
Borone, Carla
Brunner, Han G.
Carle, Georgas F.
Dallapiccola, Bruno
Paepe, Anne de
Floege, Barbara
Halfhide, Melissa Lees
Hall, Bryan
Hennekam, Raoul C.
Hirose, Tatsou
Jans, Ab
Juppner, Harald
Kim, Chong Ae
Keppler-Noreuil, Kim
Kohlschuetter, Alfried
LaCombe, Didier
Lambert, MArie
Lemyre, Emmanuelle
Letteboer, Tom
Peltonen, Leena
Ramesar, Rajkumar S.
Romanengo, Marta
Somer, Hannu
Steichen-Gersdorf, Elisabeth
Steinman, beat
Sullivan, Beth
Superti-Firga, Andrea
Swoboda, Walter
Boogaard, MArie-Jose van der
Hul, Wim van
Vikkula, Miika
Votruba, Marcela
Zabel, Bernhard
Garcia, Teresa
Baron, Roland
Olsen, Bjorn R.
Warman, Matthew L.
Source :: Cell. Nov 16, 2001, Vol. 107 Issue 4, p513, 12 p.
Publication Year :: 2001
Abstract: Research has been conducted on the low peak mass that presents significant risk factor for osteoporosis. The effect of the LRP5 encoding the low-density lipoprotein receptor-related protein 5 on the bone mass accrual during growth has been investigated and the results are reported.

Subjects :: Cell research -- Analysis
Proteins -- Physiological aspects
Lipoproteins -- Physiological aspects
Bones -- Growth
Biological sciences

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