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On the role of RNA amplification in dsRNA-triggered gene silencing

Authors :
Sijen, Titia
Fleenor, Jamie
Simmer, Femke
Thijssen, Karen L.
Parrish, Susan
Timmons, Lisa
Plasterk, Ronald H. A.
Fire, Andrew
Source :
Cell. Nov 16, 2001, Vol. 107 Issue 4, p465, 12 p.
Publication Year :
2001

Abstract

Research has been conducted on the trigger RNA amplification. The effect of this amplification on the RNA interference in Caenorhabditis elegans has been investigated and the results indicate that the amplification mechanism augments the RNA interference-based surveillance potency.

Details

ISSN :
00928674
Volume :
107
Issue :
4
Database :
Gale General OneFile
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
edsgcl.80848165