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Neural correlates of traumatic memories in posttraumatic stress disorder: a functional MRI investigation. (Brief Report)
- Source :
- American Journal of Psychiatry. Nov, 2001, Vol. 158 Issue 11, p1920, 3 p.
- Publication Year :
- 2001
-
Abstract
- Objective: The neuronal circuitry underlying posttraumatic stress disorder (PTSD) was studied in traumatized subjects with and without PTSD. Method: Traumatized subjects with (N=9) and without (N=9) PTSD were studied by using the script-driven symptom provocation paradigm adapted to functional magnetic resonance imaging at a 4-T field strength. Results: PTSD subjects showed significantly less activation of the thalamus, the anterior cingulate gyrus (Brodmann's area 32), and the medial frontal gyrus (Brodmann's area 10/11) than did the comparison subjects. Conclusions: The findings suggest anterior cingulate, frontal, and thalamic involvement in the neuronal circuitry underlying PTSD. (Am J Psychiatry 2001; 158:1920-1922)
Details
- ISSN :
- 0002953X
- Volume :
- 158
- Issue :
- 11
- Database :
- Gale General OneFile
- Journal :
- American Journal of Psychiatry
- Publication Type :
- Periodical
- Accession number :
- edsgcl.80597710