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Salts induce structural changes in elongation factor 1alpha from the hyperthermophilic archaeon Sulfolobus solfataricus: a Fourier transform infrared spectroscopic study

Authors :
Tanfani, Fabio
Scire, Andrea
Masullo, Mariorosario
Raimo, Gennaro
Bertoli, Enrico
Bocchini, Vincenzo
Source :
Biochemistry. Nov 6, 2001, Vol. 40 Issue 44, p13143, 6 p.
Publication Year :
2001

Abstract

Results show that sodium cation induces GTPase activity and the anions modulate the enzyme activity through destabilization of regions of elongation factor 1-alpha from Sulfolobus solfataricus. Infrared analysis indicate particular regions of the polypeptide undergoing structural confromational changes.

Details

ISSN :
00062960
Volume :
40
Issue :
44
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.80378860