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Treatment‐naïve people living with HIV aged 50 years or older in Beijing, China, 2010–2020: joinpoint regression model analysis of surveillance data

Authors :
Wang, Duoduo
Zhou, Mengge
Wang, Peicheng
Zhang, Jinjuan
Mi, Yuanqi
Cheng, Feng
Liu, Jufen
Source :
Journal of the International AIDS Society. December, 2023, Vol. 26 Issue 12
Publication Year :
2023

Abstract

: Introduction: As they age, people living with HIV (PLWH) must face new challenges, such as accelerated ageing and higher rates of comorbidities. This study described the characteristics of HIV acquisition among treatment‐naïve PLWH aged ≥50 years and Methods: In this cross‐sectional study, differences in HIV‐related and non‐HIV‐related characteristics were compared using the t‐test, Mann−Whitney U test and chi‐square test. Temporal trend data were analysed via joinpoint regression. A multivariate logistic regression model was conducted to analyse the associated factors with PLWH having one or more comorbidities. Results: The proportion of PLWH aged ≥50 years has significantly increased since 2013, with a corresponding increase in homosexual transmission in this age group over the past decade. The proportion of individuals with CD4 counts Conclusions: Due to the persistent burden of HIV‐related characteristics or symptoms and the increasing prevalence of coexisting comorbidities among treatment‐naïve PLWH aged ≥50 years, physicians should provide the highest‐quality screening, prevention, treatment and management of coexisting comorbidities, adopting a multidisciplinary approach.<br />INTRODUCTION Antiretroviral therapy (ART) has transformed human immunodeficiency virus (HIV) from a uniformly fatal to a chronic condition [1]. However, people living with HIV (PLWH) still have shorter life expectancies [...]

Details

Language :
English
ISSN :
17582652
Volume :
26
Issue :
12
Database :
Gale General OneFile
Journal :
Journal of the International AIDS Society
Publication Type :
Academic Journal
Accession number :
edsgcl.791075653
Full Text :
https://doi.org/10.1002/jia2.26193