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Dysfunction of endothelial protein C activation in severe meningococcal sepsis

Authors :
Faust, Saul N.
Levin, Michael
Harrison, Odile B.
Goldin, Robert D.
Lockhart, Marion S.
Kondaveeti, Sheila
Laszik, Zoltan
Esmon, Charles T.
Heyderman, Robert S.
Source :
The New England Journal of Medicine. August 9, 2001, Vol. 345 Issue 6, p408, 9 p.
Publication Year :
2001

Abstract

Protein C is not activated as it normally should be in patients with severe meningococcal infection. This may explain why these patients develop abnormal blood clots, since protein C is a naturally occurring anticoagulant in the body.

Details

ISSN :
00284793
Volume :
345
Issue :
6
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.77331394