Mutational analysis of the K (super)+ -competitive inhibitor site of gastric H,K-ATPase

Authors :: Vagin, Olga
Munson, Keith
Lambrecht, Nils
Karlish, Steven J. D.
Sachs, George
Source :: Biochemistry. June 26, 2001, Vol. 40 Issue 25, p7480, 11 p.
Publication Year :: 2001
Abstract: Research has been conducted on the gastric H,K-ATPase inhibited selectively. The effect of the concervative and nonconcervative carbaxylic residue mutations on the the ion and protonated imidazo[1,2alpha]pyridine affinity has been investigated.

Subjects :: Biochemistry -- Research
Adenosine triphosphatase -- Research
Gene mutations -- Research
Pyridine -- Research
Protons -- Research
Imidazole -- Research
Biological sciences
Chemistry

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