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A Method for Filling Complex Polymeric Microfluidic Devices and Arrays
- Source :
- Analytical Chemistry. July 1, 2001, Vol. 73 Issue 13, 3193
- Publication Year :
- 2001
-
Abstract
- This paper describes an improved method for filling microfluidic structures with aqueous solutions. The method, channel outgas technique (COT), is based on a filling procedure carried out at reduced pressures. This procedure is compared with previously reported methods in which microfluidic channels are filled either by using capillary forces or by applying a pressure gradient at one or more empty reservoirs. The technique has proven to be [is greater than] 90% effective in eliminating the formation of bubbles within microfluidic networks. It can be applied to many devices, including those containing PDMS-terminated channel features, a single channel inlet, and three-dimensional arrays.
- Subjects :
- Chemistry, Analytic -- Research
Polymers -- Analysis
Chemistry
Subjects
Details
- ISSN :
- 00032700
- Volume :
- 73
- Issue :
- 13
- Database :
- Gale General OneFile
- Journal :
- Analytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.76930000