The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation

Authors :: Aravind, L.
Source :: Trends in Biochemical Sciences. May, 2001, Vol. 26 Issue 5, 273
Publication Year :: 2001
Abstract: Sequence profile analysis was used to detect a conserved globular domain in several proteins including deltex, Trip 12 and poly-ADP-ribose polymerase homologs. It was named the WWE domain after its most conserved residues and is predicted to mediate specific protein-protein interactions in ubiquitin and ADP-ribose conjugation systems.

Subjects :: Proteins -- Physiological aspects
Globular proteins -- Physiological aspects
Ubiquitin -- Physiological aspects
Biological sciences
Chemistry

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