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The -48 C/T polymorphism in the presenilin 1 promoter is associated with an increased risk of developing Alzheimer's disease and an increased Aβ load in brain
- Source :
- Journal of Medical Genetics. June 2001, Vol. 38 Issue 6, 353
- Publication Year :
- 2001
-
Abstract
- Mutations in the presenilin 1 gene (PS1) account for the majority of early onset, familial, autosomal dominant forms of Alzheimer's disease (AD), whereas its role in other late onset forms [...]
Details
- Language :
- English
- ISSN :
- 00222593
- Volume :
- 38
- Issue :
- 6
- Database :
- Gale General OneFile
- Journal :
- Journal of Medical Genetics
- Publication Type :
- Periodical
- Accession number :
- edsgcl.76559739