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Use of Cryopreserved Cadaver Vein Allograft (CAVF) Precludes Renal Transplantation Due to Allosensitization
- Source :
- Nephrology Nursing Journal. June 2001, Vol. 28 Issue 3, 352
- Publication Year :
- 2001
-
Abstract
- CAVF has been proposed as a superior access conduit in the problem access population. The potential advantage is the reported 80% endothelial cell viability that theoretically leads to fewer thromboses and greater patency. The authors reviewed a series of 20 consecutive patients who received CAVY as access. At 3.1 months postgraft placement, mean panel reactive antibody (PRA) for this group was 77.8%. Retrospective pregraft PRA values were found on seven patients who were on the transplant waiting list, and six of these were found to have been unsensitized ([is less than] 0.05%) prior to CAVF. Mean PRA in these patients post CAVF was 92.3%. The authors concluded that CAVF use can broadly allosensitize recipients, precluding transplantation in the vast majority. Therefore, CAVF should not be used in potential transplant recipients.<br />Use of Cryopreserved Cadaver Vein Allograft (CAVF) Precludes Renal Transplantation Due to Allosensitization. G. Lipkowitz, B. Benedetto, R. Madden, A. Kurbanov, D. Hull, M. Germain, L. Bow, & M. Miller. [...]
Details
- Language :
- English
- ISSN :
- 1526744X
- Volume :
- 28
- Issue :
- 3
- Database :
- Gale General OneFile
- Journal :
- Nephrology Nursing Journal
- Publication Type :
- Periodical
- Accession number :
- edsgcl.76512467